Peptide Combinations
Stacking Guides
Some peptides work better together. These are the combinations that make sense — with explanations of why each pairing works, not just what to take.
What is peptide stacking?
Stacking means running more than one peptide at a time, chosen intentionally because their mechanisms complement each other. Done right, you get outcomes neither peptide could produce alone.
Done wrong, you’re just taking more things. These guides exist so you understand the why behind every combination — not just the what.
Browse by goal
4 stacks
Skin + Glow
Stacks targeting collagen production, skin repair, and overall complexion quality.
BPC-157
GHK-Cu
Epithalon
5 stacks
Repair + Recovery
Combinations for injury healing, tendon and ligament repair, and post-training recovery.
BPC-157
TB-500
Thymosin Alpha-1
4 stacks
Longevity
Stacks focused on cellular health, telomere support, and slowing the biological aging process.
Epithalon
Humanin
MOTS-c
4 stacks
Weight + Metabolism
Combinations that support fat metabolism, insulin sensitivity, and body composition goals.
Semaglutide
AOD-9604
MOTS-c
4 stacks
Hormones + Balance
Growth hormone support, hormonal rhythm, and endocrine optimization stacks.
CJC-1295
Ipamorelin
Tesamorelin
3 stacks
Energy + Focus
Cognitive and nootropic stacks for mental clarity, focus, and mood stability.
Semax
Selank
Dihexa
5 stacks
Performance
Stacks for active people focused on endurance, lean mass, and training recovery.
BPC-157
TB-500
IGF-1 LR3
5 stacks
Repair + Recovery
Combinations that support deep sleep, overnight repair, and nervous system recovery.
CJC-1295
Ipamorelin
DSIP
Most popular stacks
The combinations the All Pepped Up community runs most — and why.
Hormones + Performance
Beginner
The Classic GH Stack
CJC-1295
Ipamorelin
CJC-1295 extends the GH pulse window while Ipamorelin triggers a clean, selective GH release. Together they produce a stronger, more sustained pulse than either does alone — without the cortisol or prolactin spike of older secretagogues.
- Collagen support
- Skin cell regeneration
- Anti-aging at cellular level
12 weeks on, 4 off
Repair + Recovery
Beginner
The Repair Stack
BPC-157
TB-500
BPC-157 works locally — accelerating healing at the injury site. TB-500 works systemically — promoting cell migration and tissue repair body-wide. Together they cover both mechanisms of healing.
- Accelerated injury recovery
- Reduced inflammation
- Tendon and ligament repair
8–12 weeks, repeat after 4 off
Skin + Glow · Longevity
Beginner
The Skin + Longevity Stack
GHK-Cu
Epithalon
GHK-Cu drives collagen synthesis and skin remodeling at the tissue level. Epithalon works at the cellular level — supporting telomere length and the genes that regulate skin aging. A rare stack that addresses skin from two completely different angles.
- Collagen support
- Skin cell regeneration
- Anti-aging at cellular level
Epithalon 10-day · GHK-Cu 8–12 wks
Weight + Metabolism
Beginner
The Metabolic Stack
Semaglutide
AOD-9604
Semaglutide manages appetite and glucose regulation via GLP-1 pathways. AOD-9604 targets fat metabolism directly without the blood sugar effects of full GH. The combination addresses both appetite and fat oxidation simultaneously.
- Appetite regulation
- Targeted fat metabolism
- Metabolic flexibility
Ongoing with dose titration
Want to build your own?
Stacking should be intentional, not random. Here’s how to think about it.
Have a stack you want to share with the community?
For first-timers
New to stacking? Start simple.
If you’re in your first few cycles, the CJC-1295 + Ipamorelin stack is where most people begin — well-studied, forgiving, and effective. Read the full beginner guide before adding anything else.
What the community is running
Real protocols from real members — logged and shared openly.
Sarah
Week 8 of 12
Goal — Skin + Longevity
GHK-Cu
Epithalon
BPC-157
“Skin texture has noticeably improved. Sleep is deeper than it’s been in years.”
Read full log →
James
Week 4 of 8
Goal — Injury Recovery
BPC-157
TB-500
“Shoulder that’s been problematic for 2 years is finally responding. Physio noticed the difference.”
Read full log →
Sarah
Week 8 of 12
Goal — Skin + Longevity
GHK-Cu
Epithalon
BPC-157
“Appetite is manageable for the first time. Energy hasn’t dropped which I was worried about.”
Read full log →
Ready to build your protocol?
Start with the encyclopedia to understand each peptide, then come back here to combine them.